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Bradykinin produced concentration dependent vasorelaxations in male and femalePCAs when gassed with either 95%O2or air, with no differences in the Rmaxor EC50. Tiron increased thepotency of bradykinin only when gassed with 95%O2in PCAs from both sexes. At 95%O2, catalase pre vented the leftward shift caused by Tiron in both sexes indicating that catalase prevented the formationof H2O2by Tiron.
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