S. And Holdsworth, R. E. Consequently, yeast cells were subjected to a series of increasing osmolality levels induced by sorbitol, designed to replicate high gravity conditions. These conditions were shown to have a negative impact on yeast viability and vitality, although cell genome integrity was unaffected. In addition, cells responded to osmotic pressure by modifying membrane components leading to a change in fluidity, and by promoting glycerol production.
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